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1007/s00586-014-3675-2
DDX3 inhibitor
Formula: C19H27N3O4
CAS Number: 1141777-14-1
InChiKey: FZEXGDDBXLBRTD-AYIMTCTASA-N
ERRα antagonist-1 Catalog No.:M15324-2 1007/s00586-014-3675-2ERR antagonist 1 (Compound A) is a selective and high affinity estrogen related receptor (ERR) antagonist. ERR antagonist 1 inhibits interaction of ERR with Proliferator activated Receptor Coactivator 1 (PGC 1) and PGC 1, the IC50 values are 170 nM and 180 nM, respectively. ERR antagonist 1 does not inhibit the interaction of either ERR or ERR with PGC 1 and PGC 1 coactivator, and also does not inhibit interaction of ER or ER with PGC 1 or SRC 1.
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