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Semapimod tetrahydrochloride (disodium salt) Formula: C22H16F3N3O2S

SKU: 27773761600

4.4
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Description

Formula: C22H16F3N3O2S

Smiles: COC1=CC(C=CC(=O)OC)=CC=C1O

InChi: InChI=1S/C22H17F2N5OS/c1-14(21-28-20(10-31-21)16-4-2-15(9-25)3-5-16)22(30

O-Desmethylvenlafaxine succinate hydrate

K/c1-16(2)12(15(21)22)18-13(20)11(14(18)23-16)17-10(19)8-9-6-4-3-5-7-9

Semapimod tetrahydrochloride (disodium salt) Formula: C22H16F3N3O2SSemapimod tetrahydrochloride (CNI 1493), an inhibitor of proinflammatory cytokine production, can inhibit TNF , IL 1, and IL 6. Semapimod tetrahydrochloride inhibits TLR4 signaling (IC500. 3 M). Semapimod tetrahydrochloride inhibits p38 MAPK and nitric oxide production in macrophages. Semapimod tetrahydrochloride has potential in a variety of inflammatory and autoimmune disorders. Product information CAS Number: 164301 51 3 Molecular Weight: 890. 74

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