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Non-hinge-binding pyrazolo[1
(2012) ACS Chem Biol
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PRMT1-2e - Protein Arginine Methyltransferase 1 (PRMT1) Inhibitor. CAS# 17328-16-4 279 Non-hinge-binding pyrazolo[1PRMT1 2e, CAS No. 17328 16 4, is a potent, specific and cell permeable inhibitor of protein arginine methyltransferase 1 (PRMT1) with an IC50 ~1. 5 M. It has no activity against CARM1 and Set7 9 methyltransferases. It inhibits growth of MCF7a breast cancer cells (IC50 ~1. 97 M) and LNCaP prostate cancer cells (IC50 ~4. 49 M). It can attenuate androgen induced gene expression in LNCaP cells. Product information CAS Number: 17328 16 4 Molecular Weight: