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Smiles: CN1C=C(C=C(C)C1=O)C1=CC=C2N=C(C3CCOCC3)N(CCOC(F)(F)F)C2=C1
αvβ8 and α5β1
Ph+ human ALL xenografts responds to FTY720 with an 80 % reduction in overall disease if treatment has been initiated early on
Expert Opin Drug Discov
InChiKey: DNFUGMMXLDVIQL-JXKBJQKMSA-N
EHT 5372 Catalog No.:M16773-C Smiles: CN1C=C(C=C(C)C1=O)C1=CC=C2N=C(C3CCOCC3)N(CCOC(F)(F)F)C2=C1EHT 5372 is a highly potent and selective inhibitor of DYRKs family kinases with IC50s of 0. 22, 0. 28, 10. 8, 93. 2, 22. 8, 88. 8, 59. 0, 7. 44, 221 nM for DYRK1A, DYRK1B , DYRK2 DYRK3 CLK1, CLK2, CLK4, GSK 3, GSK 3. Product information CAS Number: 1425945 63 6 Molecular Weight: 404. 27 Formula: C17H11Cl2N5OS Chemical Name: methyl 9 [(2,4 dichlorophenyl)amino] [1,3]thiazolo[5,4 f]quinazoline 2 carboximidate Smiles:
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US$ 154.00