I can block it with either Gemrazer or Akoum Hellhound, or even with both
So long as you have a land that produces more than one mana at a time, you can instantly generate infinite mana, though you then need something to put it into, like a Fireball for instance
If I appear to be overlooking anything regarding either of these combos, please let me know since I always had a fascination with various combos (especially ones that go infinite).
Just need to not get Murktide Regented
Knowledge Exploitation Commanders like Tetsuko Umezawa, Fugitive or Bilbo, Retired Burglar benefit a lot from running Knowledge Exploitation due to their nature to hit their opponents with ease
Nelly Borca is the main commander, providing card advantage and making creatures unable to block