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a rebeccamycin analogue
MS023 potently reduces cellular levels of H4R3me2a in MCF7 and HEK293 cells by inhibiting PRMT1/6 methyltransferase activity with IC50 of 9 nM and 56 nM
the inhibition of phosphorylation of mTOR substrates and reduced protein synthesis in HL-60 cells
CAS Number: 489-32-7
IC50: transforming growth factor-beta receptor 1 (TGFbR1)
Coenzyme Q9 omide-PEG4-COOH a rebeccamycin analogueCoenzyme Q9 (Ubiquinone Q9), the major form of ubiquinone in rodents, is an amphipathic molecular component of the electron transport chain that functions as an endogenous antioxidant. Coenzyme Q9 attenuates the diabetes induced decreases in antioxidant defense mechanisms. Coenzyme Q9 improves left ventricular performance and reduces myocardial infarct size and cardiomyocyte apoptosis. Product information CAS Number: 303 97 9 Molecular Weight: 795. 23
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