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Dasatinib N-oxide - CAS# 910297-52-8 guat BRD5529 is a selective CARD9-E3

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Description

BRD5529 is a selective CARD9-E3 ubiquitin ligase TRIM62 protein-protein interaction inhibitor with an IC50 of 8

14bS)-11-carboxy-4

the A66 on SK-OV-3 tumour tissue is tested using a single dose of 100 mg/kg of body weight to determine whether a long-lasting effect of the drug could be achieved on target tissues

It causes growth inhibition of normal and transformed cells but does not induce cell death

N-Bromoacetyl-β-alanine is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

Dasatinib N-oxide - CAS# 910297-52-8 guat BRD5529 is a selective CARD9-E3Dasatinib N oxide is a minor metabolite of Dasatinib. Dasatinib is a potent and orally active dual Src Bcr Abl inhibitor. Product information CAS Number: 910297 52 8 Molecular Weight: 504. 00 Formula: C22H26ClN7O3S Chemical Name: 4 [6 ({5 [(2 chloro 6 methylphenyl)carbamoyl] 1,3 thiazol 2 yl}amino) 2 methylpyrimidin 4 yl] 1 (2 hydroxyethyl)piperazin 1 ium 1 olate Smiles: CC1N=C(C=C(NC2=NC=C(S2)C(=O)NC2=C(Cl)C=CC=C2C)N=1)N1CC[N+]([O ])(CCO)CC1

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