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Aldebeyan SA
Horm Res Paediatr
Solubility: DMSO: 6 mg/mL(9
InChi: InChI=1S/C22H28FN3O6S
Formula: C28H27N5O2S
SCH900776 lrestatin Aldebeyan SASCH900776, also known as MK 8776. is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities. Chk1 inhibitor SCH 900776 specifically binds to and inhibits Chk1, which may result in tumor cells bypassing Chk1 dependent cell cycle arrest in the S and G2 M phases to undergo DNA repair prior to entry into mitosis; tumor cells may thus be sensitized to the DNA damaging effects of ionizing
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