Dovitinib-D8 zine-d3 It is a good chemical

It is a good chemical tool to enable interrogation of GPR39 signaling in different cellular contexts

11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-7-yl]oxy}-3-carboxy-1-oxopropan-2-yl]carbamoyl}-2-aminobutanoic acid

InChi: InChI=1S/C15H17NO5/c17-15(20-13-6-4-2-1-3-5-7-13)21-14-10-8-12(9-11-14)16(18)19/h1-2

20)21)23-17(24-16)22-14-5-3-2-4-6-14

1 μM in direct measurement of pyruvate transport into rat liver and yeast mitochondria

Dovitinib-D8 zine-d3 It is a good chemicalDovitinib D8 (CHIR 258 D8) is the deuterium labeled Dovitinib. Dovitinib (CHIR 258) is a multi targeted tyrosine kinase inhibitor with IC50s of 1, 2, 8 9, 10 13 8, 27 210 nM for FLT3, c Kit, FGFR1 FGFR3, VEGFR1 VEGFR2 VEGFR3 and PDGFR PDGFR, respectively. Product information CAS Number: 1246819 84 0 Molecular Weight: 400. 48 Formula: C21H21FN6O Chemical Name: 4 amino 5 fluoro 3 {6 [4 methyl(2,2,3,3,5,5,6,6 H)piperazin 1 yl] 1H 1,3 benzodiazol 2 yl}