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10-20)17(22)24-9-13-4-6-19-7-5-14(15(13)19)25-16(12)21/h3-4
WO 2017024317 A2
5-5 µM concentration in vitro and in cellular assays
thereby inhibiting DNA and RNA synthesis
Cell permeant
MitoBloCK-10 ehyde 3-phosphate 10-20)17(22)24-9-13-4-6-19-7-5-14(15(13)19)25-16(12)21/h3-4MitoBloCK 10 (MB 10) is the first small molecule modulator to attenuate protein associated motor (PAM) complex activity. MitoBloCK 10 (MB 10) inhibits Tim44 (C terminal domain) binding to the precursor and to Hsp70. Product information CAS Number: 394694 98 5 Molecular Weight: 293. 27 Formula: C12H8FN3O3S Chemical Name: 3 fluoro N' [(1E) (5 nitrothiophen 2 yl)methylidene]benzohydrazide Smiles: [O ][N+](=O)C1=CC=C( C=N NC(=O)C2C=C(F)C=CC=2)S1 InChiKey:
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