AZ505 is a potent and highly selective inhibitor of SMYD2 with potential anticancer activity
Hyperforin dicyclohexylammonium salt (Hyperforin DCHA) has a multi-directional mechanism of action
anti-infammatory
Treatment of human pancreatic cancer cells with CBL0137 hydrochloride results in a dose dependent reduction of protein and mRNA levels of RRM1 and RRM2
Pregnenolone and progesterone are avidly metabolized to 5α-pregnan-3β
Lei-Dab7 TFA ximab AZ505 is a potent andLei Dab7 TFA is a high affinity, selective KCa2. 2 (SK2) channel blocker (Kd=3. 8 nM). Lei Dab7 TFA exhibits >200 fold selectivity for KCa2. 2 over KCa2. 1, KCa2. 3, KCa3. 1, Kv and Kir2. 1. Lei Dab7 TFA increases theta burst responses and increases LTP in rat hippocampal slices in vitro. Product information Molecular Weight: 3508. 10 Formula: C143H239F3N46O41S6 Chemical Name: (3S, 6S, 9S, 12R, 15S, 18S, 21S, 27S, 30S, 36S, 39R, 42S, 48S) 48 (((S) 6