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RN-1747 - CAS# 1024448-59-6 acipran Hydrochloride TC11 shows in vivo activity

SKU: 87354549172

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Description

TC11 shows in vivo activity against multiple myeloma cell line KMS34 tumor xenografts in ICR/SCID mice

Biotin-PEG2-Mal is a PEG-based PROTAC linker can be used in the synthesis of PROTAC

InChi: InChI=1S/C25H27NO

thereby blocking VEGF-signaling

Formula: C32H42N4O8S

RN-1747 - CAS# 1024448-59-6 acipran Hydrochloride TC11 shows in vivo activityRN 1747 is a selective TRPV4 agonist with EC50s of 0. 77 M, 4. 0 M and 4. 1 M for hTRPV4, mTRPV4 and rTRPV4, respectively. RN 1747 also antagonizes TRPM8 with IC50 of 4 M. Product information CAS Number: 1024448 59 6 Molecular Weight: 395. 86 Formula: C17H18ClN3O4S Chemical Name: 1 benzyl 4 (4 chloro 2 nitrobenzenesulfonyl)piperazine Smiles: [O ][N+](=O)C1=CC(Cl)=CC=C1S(=O)(=O)N1CCN(CC2C=CC=CC=2)CC1 InChiKey: ZNLVYSJQUMALEO UHFFFAOYSA N InChi:

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