![GW791343 trihydrochloride - CAS# 309712-55-8 Catalog No.:M10057-2 2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-4H](https://cdn.shopify.com/s/files/1/0389/1897/9723/products/M10057_1621561252.gif?v=1742876804)
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2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-4H
M5 positive allosteric modulator (PAM) with EC50 of 6
Cheney et al (2007) Identification and structure-activity relationships of substituted pyridones as inhibitors of Pim-1 kinase
Formula: C24H25N5O
InChiKey: OGNYUTNQZVRGMN-UHFFFAOYSA-N
GW791343 trihydrochloride - CAS# 309712-55-8 Catalog No.:M10057-2 2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-2-methyl-4HGW791343 is a P2X7 allosteric modulator. GW791343 exhibits species specific activity; acts as a negative allosteric modulator of human P2X7 (pIC50 = 6. 9 7. 2) and a positive allosteric modulator of rat P2X7. Product information CAS Number: 309712 55 8 Molecular Weight: 483. 81 Formula: C20H27Cl3F2N4O Synonym: GW 791343 trihydrochloride GW 791343 trihydrochloride Chemical Name: 2 [(3,4 difluorophenyl)amino] N {2 methyl 5 [(piperazin 1
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