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IN-1130 nirixin InChiKey: FPEIJQLXFHKLJV-UHFFFAOYSA-N

SKU: 91125431501

4.1
USD120.00 USD167.00

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Description

InChiKey: FPEIJQLXFHKLJV-UHFFFAOYSA-N

IN-1130 nirixin InChiKey: FPEIJQLXFHKLJV-UHFFFAOYSA-NIN 1130 is a highly selective transforming growth factor type I receptor kinase (ALK5) inhibitor with an IC50 of 5. 3 nM for ALK5 mediated Smad3 phosphorylation. IN 1130 inhibits ALK5 phosphorylation of casein (IC50=36 nM) and p38 mitogen activated protein kinase (IC50=4. 3 M). IN 1130 suppresses renal fibrosis in obstructive nephropathy and blocks breast cancer lung metastasis. Product information CAS Number: 868612 83 3 Molecular Weight: 420. 47

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