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DCLK1-IN-1 has a favorable pharmacokinetic profile in mice
One of the concerns for using glucose transport inhibitors is that the inhibitor might produce hyperglycemia in the treated mice
7 mg/dL vs 655
Scutellarin can inhibit HCC cell metastasis in vivo
AX15836 shows similar intracellular potency (4–9 nM) across all cells tested
m-PEG5-Tos Catalog No.:M14234-2 DCLK1-IN-1 has a favorable pharmacokineticm PEG5 Tos is a derivative of silybin ethers, extracted from patent CN105037337A (compound III c). m PEG5 Tos is a PEG based PROTAC linker can be used in the synthesis of Silymarin (HY W043277). Product information CAS Number: 80755 67 5 Molecular Weight: 406. 49 Formula: C18H30O8S Chemical Name: 2,5,8,11,14 pentaoxahexadecan 16 yl 4 methylbenzene 1 sulfonate Smiles: CC1C=CC(=CC=1)S(=O)(=O)OCCOCCOCCOCCOCCOC InChiKey: ARGVXLRPEZMWEQ UHFFFAOYSA N InChi:
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