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Pardoprunox acts as a partial agonist in the induction of [(35)S]GTPgammaS binding (intrinsic activity of 67%
InChi: InChI=1S/C59H84N18O14/c1-31(2)22-40(49(82)68-39(12-8-20-64-57(60)61)56(89)77-21-9-13-46(77)55(88)75-76-58(62)90)69-54(87)45(29-91-59(3
2007 Dec 10
Smiles: O[C@@H]1[C@H]([C@@H](O)[C@@H](CO)O[C@H]1S[C@@H]1O[C@H](CO)[C@H](O)[C@@H]([C@H]1O)N1C=C(N=N1)C1=CC(F)=CC=C1)N1C=C(N=N1)C1=CC(F)=CC=C1
Galeterone (TOK-001) is both a CYP17A1 inhibitor and androgen receptor antagonist and the similarity of these binding modes is likely the reason for this dual mechanism of action
DOTA derivative Size:Solid 2 mg Pardoprunox acts as a partialDOTA derivative is a benxyl derivative of the cyclic tosamide; can be nitrated directly; is more convenient to incorporate the nitro group after deprotection lithium aluminum hydride. Product information CAS Number: 153777 70 9 Molecular Weight: 879. 14 Formula: C43H50N4O8S4 Chemical Name: 2 benzyl 1,4,7,10 tetrakis(4 methylbenzenesulfonyl) 1,4,7,10 tetraazacyclododecane Smiles:
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