Docetaxel (Trihydrate) Size:Solid 2 mg Smiles: COC1C=C(NC2=NC3=CC=CC=C3N=C2NS(=O)(=O)C2C=C(C=CC=2)NC(=O)C(C)(C)N)C(Cl)=CC=1

Smiles: COC1C=C(NC2=NC3=CC=CC=C3N=C2NS(=O)(=O)C2C=C(C=CC=2)NC(=O)C(C)(C)N)C(Cl)=CC=1

AZ13337019

The SP/NK1-R complex dissociates in acidified endosomes

Front Immunol

InChiKey: HDTKLZINZGEPFG-UHFFFAOYSA-N

Docetaxel (Trihydrate) Size:Solid 2 mg Smiles: COC1C=C(NC2=NC3=CC=CC=C3N=C2NS(=O)(=O)C2C=C(C=CC=2)NC(=O)C(C)(C)N)C(Cl)=CC=1Docetaxel, also known as RP 56976, is a semi synthetic, second generation taxane derived from a compound found in the European yew tree Taxus baccata. Docetaxel displays potent and broad antineoplastic properties; it binds to and stabilizes tubulin, thereby inhibiting microtubule disassembly which results in cell cycle arrest at the G2 M phase and cell death. This agent also inhibits pro angiogenic factors such as vascular endothelial growth factor