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InChi: InChI=1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9
Chemical Name: 2-[(1R
1 and 1mg/kg/day doses
Smiles: C[C@H](NC)C(=O)N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C1=NC(=CS1)C(=O)C1=CC(=CC=C1)OCCOCCOCCOCC(=O)NC1=NC2=CC=C(N=C2S1)C1=CC(=CC=C1)C(=O)NC1=CC(=C(CN2CCN(CC2)CC)C=C1)C(F)(F)F
Hhat inhibitor could offer a new treatment modality for cancers characterized by Shh overexpression and extremely poor prognoses
RPR-260243 15905 InChi: InChI=1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9RPR 260243, a potent activator of human ether a go go related gene (hERG), slows deactivation and attenuates inactivation of hERG1 channels. RPR260243 modified HERG currents are inhibited by Dofetilide (IC50=58 nM). RPR260243 displays no activator like effects on other voltage dependent ion channels, including the closely related ERG3 K+ channel. Product information CAS Number: 668463 35 2 Molecular Weight: 510. 50 Formula: C28H25F3N2O4 Chemical Name: