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NNC 55-0396 - CAS# 357400-13-6 203580 Hydrochloride ASP3026 inhibited the growth of

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Description

ASP3026 inhibited the growth of NCI-H2228

130 nM) in human umbilical vein endothelial cells

Cytosine-1-β-D-ribofuranoside

CPI203 is an analog of JQ-1 but has shown superior bioavailability with oral or intraperitoneal (IP) administration

Chemical Name: (2R)-2-[4-(2-methylpropyl)phenyl]propanoic acid

NNC 55-0396 - CAS# 357400-13-6 203580 Hydrochloride ASP3026 inhibited the growth ofNNC 55 0396 is a T type calcium channel blocker. NNC 55 0396 inhibits angiogenesis via suppression of hypoxia inducible factor 1 signal transduction. NNC 55 0396 suppressed mitochondrial reactive oxygen species mediated HIF 1 expression as well as stabilization by inhibiting protein synthesis in a dose dependent manner. NNC 55 0396 inhibited tumor induced angiogenesis in vitro and in vivo by suppressing HIF 1 stability. NNC 55 0396 could be a

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