GBR-12935 HCl - CAS# 67469-81-2 Catalog No.:M7140-2 CHIR-090 at low nM levels

CHIR-090 at low nM levels inhibits LpxC orthologues from diverse Gram-negative pathogens

InChi: InChI=1S/C16H13Cl2N3O/c17-12-7-4-8-13(18)14(12)20-16-19-9-10-21(16)15(22)11-5-2-1-3-6-11/h1-8H

a protein known to be elevated in a variety of tumors

Shinya Kida

Madrasin (10-30 μM

GBR-12935 HCl - CAS# 67469-81-2 Catalog No.:M7140-2 CHIR-090 at low nM levelsGBR 12935 HCl, CAS No. 67469 81 2, is a piperazine derivative which is a potent and selective dopamine reuptake inhibitor. It was originally developed in its 3H radiolabelled form for the purpose of mapping the distribution of dopaminergic neurons in the brain by selective labelling of dopamine transporter proteins. This has led to potential clinical uses in the diagnosis of Parkinson's disease, although selective radioligands such as Ioflupane (I)